Inhibition of excessive Toll-like receptor 4 (TLR4) signaling is a therapeutic approach pursued for many inflammatory diseases. We report that Mannoside Glycolipid Conjugates (MGCs) selectively ...

Sulforaphane (SFN) has various biological effects on type 2 diabetes mellitus (T2DM). However, only a few studies have attempted to elucidate the effect of sulforaphane on intestinal microflora in ...

In a study recently published in the journal Nature Chemical Biology, researchers reveal that two reactive byproducts of sugar metabolism—methylglyoxal and its metabolite lactoylglutathione ...

How alterations in cell metabolism translate into specific developmental gene programs remains a major question. This study shows that forcing OXPHOS metabolism reprograms mouse embryonic stem cells ...