Sterols, such as cholesterol in our bodies or ergosterol in yeast cells, are among the most abundant lipids in eukaryotic ...

Seed plants, such as soybeans, store large amounts of protein in specialized organelles called protein storage vacuoles.

Viruses are natural delivery systems for nucleic acids, but they have several significant drawbacks: They aren’t targeted to any one cell type, for instance, and they can’t be re-dosed—the ...

Sterols are among the most abundant lipids in eukaryotic cells, yet are synthesized through notoriously long, complex metabolic pathways. Researchers have used a novel approach to show how they ...

Metastatic colorectal cancer (mCRC) continues to pose a clinical and commercial challenge, with low 5-year survival rates and limited durable responses to existing therapies. While standard ...

CLEVELAND, Ohio - A Lorain County corrections officer was fired last month after an excessive force incident led to an inmate getting out of his cell. On Dec. 29, 2024, as jail staff served lunch ...

An unprecedented international effort to decode how cells manage the transport of chemical substances has culminated in four ...

This valuable study reports the conservation of sperm-egg envelope binding by demonstrating successful recognition of the micropyle in fish eggs by the mouse sperm. However, the evidence supporting ...

Here we report that the endoplasmic reticulum (ER)-resident SNARE Sec22b has a conserved non-fusogenic function in plasma membrane expansion. Sec22b is closely apposed to the plasma membrane SNARE ...