The HIV-1 gp120 glycoprotein is the main viral surface protein responsible for initiation of the entry process and, as such, can be targeted for the development of entry inhibitors. We previously ...

In mice, mucin-domain glycoproteins on blood vessels wane with age. Boosting their abundance in old mice firmed up the blood-brain barrier. These glycoproteins also ebb in Alzheimer’s and Huntington’s ...

Tyrosine sulfation is a post-translational modification that facilitates protein-protein interaction. Two sulfated tyrosines (Tys173 and Tys177) were recently identified within the second variable (V2 ...

Antibodies binding to hiv gp120 for treating hiv infection Source: United States Patent and Trademark Office (USPTO). Credit: Gilead Sciences Inc A patent application (Publication Number: ...

The team’s results, which show how a tiny section of the HIV-1 glycoprotein surface snaps open and shut in a millionth of a second, could help scientists design and develop broadly neutralizing ...

The trial utilized the ALVAC-HIV (vCP2438) vaccine and an adjuvanted bivalent subtype C glycoprotein 120 (gp120) vaccine, providing valuable insights into the potential for improved HIV prevention ...

A glycoprotein is a highly abundant molecule made of protein and carbohydrates. Learn about different types of glycoproteins and glycoprotein functions in immune signaling, viral infection, and cancer ...

The effects of the glycoprotein IIb/IIIa receptor inhibitor tirofiban in patients with acute ischemic stroke but who have no evidence of complete occlusion of large or medium-sized vessels have not ...

Human immunodeficiency virus envelope glycoprotein 120 (gp120) leads to hyperalgesia. Long non-coding RNAs are characterized by the lack of a protein-coding sequence and may contribute to the ...