The research indicates that reprogrammed T helper cells adopt characteristics of a new T helper cell type while preserving some of their original traits, making them “super powerful and potent ...

When Treg cells are produced, they are trained to recognize specific peptides, including self-peptides from the body. When dendritic cells present a self-peptide, the peacekeeper Treg cells trained to ...

Adoptive Cell Transfer (ACT) includes a class of immunotherapy approaches to treat cancer.  This procedure focuses on a ...

Discovery of innate immune receptor "brake" Siglec-E offers a novel therapeutic target to prevent organ transplant rejection ...

Notably, DT2035 activated both CD8+ “killer T cells” and CD4+ “helper T cells,” with the latter showing unexpected cytotoxic activity. This dual activation underscores the therapy’s ability to ...

Specifically, cytotoxic T cells target infected cells, while helper T cells and B cells drive antibody production. A critical component of this process is the delivery system- most commonly LNPs ...

A long-term study of nearly 800 patients demonstrated a strong safety profile for T cells engineered with viral vectors.

A recently developed cancer treatment called chimeric antigen receptor T-cell therapy (CAR T-cell therapy, for short) offers hope to people whose diffuse large B-cell lymphoma (DLBCL) has proved ...

If you or a loved one has diffuse large B-cell lymphoma (DLBCL) that is no longer responding to treatment or came back after treatment, chimeric antigen receptor (CAR) T-cell therapy may be an option.