Results In rats, PAS/AB and MUC2/DBA staining revealed mucus layer detachment at ischaemia which was accompanied by bacterial penetration (in EM and FISH). Human and rat studies showed that, ...

Glial depletion does not affect the ultrastructure of enteroendocrine cells, crypt base stem cells, or goblet cells. A - C) Transmission electron microscopy of enteroendocrine cells (A; EC), crypt ...

The study is published in the journal eGastroenterology. Goblet cells secrete mucus, forming a protective layer that prevents harmful pathogens from reaching the inner gut tissues.

Histological analysis, including HE and PAS staining of colon tissues, revealed extensive epithelial damage, goblet cell depletion, and inflammatory cell infiltration in DSS-treated mice.

PAS-004 is the first macrocyclic MEK inhibitor to enter human clinical trials, with an expected extended half-life which may provide better compliance rates, as well as improved efficacy in NF1 ...

We further examined for additional changes in sub-tissue level Rab7 protein expression pattern during colitis. Interestingly, immunofluorescence-based staining of Rab7 and goblet cells in colonic ...

In vivo MBFM imaging and clinical DED evaluations were performed and goblet cell density (GCD) and goblet cell area (GCA) were obtained and compared with histological GCD using periodic acid-Schiff ...

Background: Goblet Cell tumors (GCTs) of the appendix are a rare, distinct, and under studied malignancy. Since 2019 the preferred World Health Organization (WHO) terminology is Goblet Cell ...

More information: Seonghan Kim et al, Non-invasive high-contrast imaging of conjunctival goblet cells for the precision diagnosis of ocular surface diseases, The Ocular Surface (2022).