The reason for the observed mucus alterations in patients with active colitis may be higher mucus secretion as shown by the same number of, but less well filled, goblet cells—observed as smaller theca ...

Results In rats, PAS/AB and MUC2/DBA staining revealed mucus layer detachment at ischaemia which was accompanied by bacterial penetration (in EM and FISH). Human and rat studies showed that, ...

In a recent study, researchers at the University of California, San Diego, have provided new insights into the central role of goblet cells—specialized cells that line the gut—in maintaining a ...

Researchers at UC San Diego have examined the critical role of goblet cells in gut immunity and health. GCs create a mucus barrier that protects against pathogens while supporting beneficial ...

Histological analysis, including HE and PAS staining of colon tissues, revealed extensive epithelial damage, goblet cell depletion, and inflammatory cell infiltration in DSS-treated mice.

Pasithea Therapeutics to Present New Preclinical Data Showing PAS-004 Strongly Inhibits NRAS Cancer Cell Lines and Demonstrates Superior Activity in Xenograft Studies at 2024 ASCO Annual Meeting ...

2.3 Microscopic evaluation Histological staining was performed and analyzed in gill sections of all C and R fish samples. The presence of goblet cell was estimated for the different types of staining ...

We separated goblet cell density into two groups: cells with acidic mucins, as distinguished with dark blue staining, or cells with neutral mucin, as distinguished with purple staining.

More information: Seonghan Kim et al, Non-invasive high-contrast imaging of conjunctival goblet cells for the precision diagnosis of ocular surface diseases, The Ocular Surface (2022).