Dendritic cells (DCs) are increasingly being explored as cellular vaccines for tumor immunotherapy, since they provide an effective system of antigen presentation both in vitro and in vivo. An ...

EP4 Receptor Is Essential for Renal CD44+ Cell Activation In Vivo After Low-Salt and Furosemide Treatment To investigate the importance of EP4 receptor in the CD44+ cell activation after salt ...

Etokimab (I-Mab Biopharma), which is optimized for common IL-33 gene polymorphisms, has completed patient recruitment in its ...

A breach in the gut immunity and crossreactivity of the IgE antibodies with skin antigens or direct interaction with specific IgE, Fc receptors on Langerhans cells, mast cells, monocytes ...

Allergenicity In this article, we define allergenicity as the property of being able to induce a Th2 response and subsequent production of allergen-specific IgE antibodies. Usually, the presence ...

Dose-dependent, marked reductions in food intake and significant weight loss observed in obese cynomolgus monkeysBMF-650 compared favorably to published data of a leading GLP-1 RA candidateIND ...

Conclusions— The inhibition of Fc receptor–mediated phagocytosis of lovastatin is related to its effect on cholesterol biosynthesis rather than its effect on the formation of isoprenoids. An ...

These antibodies retain a fully functional Fc region, meaning they can bind to Fc receptors found on the cell surface and contribute to the protective antitumor functions of the immune system.