Insulin resistance is concomitant with type 2 diabetes, obesity, hypertension, and other features of the metabolic syndrome. Because insulin resistance is associated with cardiovascular disease ...

Now, a study published in Cell Communication and Signaling describes new molecular mechanisms to understand insulin resistance in skeletal muscle and to outline future drug targets for DM2. The ...

PPARβ/δ upregulates the insulin receptor β subunit in skeletal muscle by reducing lysosomal activity and EphB4 levels. Cell Communication and Signaling , 2024; 22 (1) DOI: 10.1186/s12964-024 ...

Get Instant Summarized Text (Gist) New molecular mechanisms linked to insulin resistance in skeletal muscle have been identified, highlighting potential drug targets for type 2 diabetes. The study ...