G-protein coupled receptors regulate hormone secretions in the pancreas ... that have seven membrane-spanning domains connected by intracellular and extracellular domains (Figure 2), and these ...

In multicellular organisms, growth factors, hormones, neurotransmitters ... producing multiple intracellular signals for every one receptor that is bound. Protein kinases such as PKA and PKC ...

A new Salk Institute study suggests estrogen-related receptors could be a key to repairing energy metabolism and muscle fatigue.

G protein-coupled receptors (GPCRs) are expressed on the surface of cells ... and why they are such attractive therapeutic targets. GPCRs have an intracellular carboxyl (C) terminus and an ...

PAMP-triggered pathways can also lead to changes in gene expression and hormone levels ... molecules into the plant cell. Intracellular plant protein complexes called nucleotide-binding domain, ...