and normalizes keratinocyte activation and differentiation, potentially mitigating epidermal barrier dysfunction," Gooderham and co-authors wrote. Effective topical treatments can be a valuable ...

The findings presented in this manuscript are fundamental, as they uncover MYL3, a member of the myosin family, as a potential entry receptor and therapeutic target for a virus that poses a major ...

have in recent years been shown to be associated with a reduced risk of developing keratinocyte-derived carcinomas (KCs) on treated areas of skin. At The American Society for Laser Medicine and ...

and to determine whether anti-tumour necrosis factor (TNF) therapy exacerbates this risk. Methods Patients with RA enrolled in the British Society for Rheumatology Biologics Register, a prospective ...

Treatment with tumour necrosis factor (TNF) inhibitors (TNFi ... Solid cancers comprised all cancers except lymphoproliferative or myeloproliferative malignancies and keratinocyte skin cancers.

[1] This detachment (called acantholysis) is due to the presence of IgG antibodies directed against keratinocyte-adhesion glycoproteins, called desmogleins (DSG), which play a critical role in ...

We focused on melanocyte-keratinocyte interaction ... (nitric oxide), NGF (nerve growth factor); PGE2/PGF2α (prostaglandin E2 and F2α), TNF-α (tumor necrosis factor-α). Regardless of the specific ...

Breast fat necrosis is a noncancerous condition that occurs when there's damage to fatty breast tissue. You can develop breast fat necrosis at any age in any area of the breast, but if you're ...

ORLANDO — Topical 5-fluorouracil and calcipotriene proved to be highly effective for superficial keratinocyte carcinomas, according to a presentation at the American Society for Dermatologic ...

The most common type of cells found in the epidermis are called keratinocytes. Basal cells are a type of keratinocyte found at the bottom of the epidermis. The basal layer is where all normal skin ...

Breast fat necrosis (tissue death or damage) is a benign condition that can cause noncancerous lumps that feel like breast cancer and look like tumors on a mammogram. It accounts for 2.75% of all ...

Repeated exposure to UVA rays is well described in the setting of cutaneous carcinogenesis, acting via a direct DNA-damaging mechanism, to cause both photo-ageing and the development of keratinocyte ...