LNP–mRNA drug products are produced by mixing the nucleic acid drug substance with various lipid components, such as phospholipids, cholesterol, PEG–lipids and ionizable lipids, resulting in a ...

The primary components of LNP–RNA are ionizable lipids, cholesterol, PEGylated lipids, and phospholipids, which together form the nanoparticle, along with the active pharmaceutical ingredient ...