A new tool called PHOTON, developed by scientists at UT Southwestern Medical Center, can identify RNA molecules at their native locations within cells—providing valuable clues to where different ...

Researchers discovered a previously unknown function of RNA, potentially opening the door to new ways to treat cancer and neurodegenerative diseases.

Scientists at St. Jude Children's Research Hospital, the National Center for Genomic Analysis and the University of Adelaide have created a single-cell RNA analysis method that is 47 times cheaper ...

RNA gene scissors (CRISPR-Cas13) are gaining significant attention as a next-generation gene therapy with fewer side effects. They can suppress infection by eliminating viral RNA, such as in ...

The researchers developed a novel LNP system that can deliver mRNA (messenger RNA) to the difficult-to-target resting CD4 + T cells (helper cells) and trigger the virus's genes to start producing ...

Topics Genome Editing Sponsored Epitranscriptomics: A New Frontier in RNA Epigenetics 25 Years After the Human Genome Project Chemical RNA modifications reveal regulatory mechanisms beyond genetic ...

Replacing PEG with PCB in lipid nanoparticles led to potent mRNA vaccines that avoided unwanted immune responses.

Chemists have demonstrated how RNA (ribonucleic acid) might have replicated itself on early Earth -- a key process in the origin of life.

Conclusions: Thus, DC-specific vaccines delivered with mRNA-LNP stimulates therapeutically effective tumor-specific immunity, offering a novel, efficient and cost-effective cancer vaccine strategy.

Phase I dose escalation trial of STX-001, an LNP-encapsulated self-replicating mRNA expressing IL-12, in patients (pts) with advanced solid tumors.. If you have the appropriate software installed, you ...