Dear Pharmacist: I heard you recommend a drug called Lactulose as a laxative, but you said it helped with brain fog too. How can it work at both ends? – J.C., Decatur, Ill. Dear J.C.: It’s true.

Lactulose oral solution is a prescription drug that’s available as the brand-name drug Generlac.It’s also available as a generic drug. Generic drugs usually cost less.

Mix 300mL of lactulose solution with 700mL of water or physologic saline, retain for 30–60 minutes. May repeat every 4–6 hours; if evacuated too promptly, may be repeated immediately.

Effect of Oral Lactulose on Clinical and Immunohistochemical Parameters in Patients with Inflammatory Bowel Disease: A Pilot Study ...

Background and Aims: Acute variceal bleed (AVB) is an important precipitating factor for development of hepatic encephalopathy (HE). However, there is paucity of data on the role of lactulose for ...

Lactulose has many benefits for HE but does have some risks and contraindications. You may also need to take it for several months. Be sure to discuss these topics with your doctor before taking ...

Fewer patients treated with rifaximin had an overt hepatic encephalopathy episode vs. those treated with lactulose (23.2% vs. 49%). Mortality rate also was lower in the rifaximin group (1.6% vs. 4 ...

Lactulose(Cholac) generic is a purgative and laxative, prescribed for chronic constipation. It works by drawing ammonia from the blood into the colon where it is removed from the body.

In patients with HE, use of rifaximin plus lactulose was associated with an increased effectiveness compared with lactulose alone (relative risk [RR], 1.30; 95% CI, 1.10-1.53; P = .002).

Adding rifaximin to lactulose treatment for acute hepatic encephalopathy did not shorten hospital length of stay but it did lower readmission rates at 180 days, study authors reported in a study ...