“If something happens and a molecule grows in abundance 200-fold in the lysosome, you would see only a two-fold increase if you look at the whole cell.” By isolating lysosomes from the rest of the ...

GCAF(TMEM251) regulates lysosome biogenesis by activating the mannose-6-phosphate pathway. Nature Communications , 2022; 13 (1) DOI: 10.1038/s41467-022-33025-1 Cite This Page : ...

A team of researchers led by Osaka University unravel a tangle of pathways involving calcium, lipids, and the degradation of damaged lysosomes that is essential for preventing crystal-induced ...