The cell and drug components give MDCs a dual mechanism-of-action that combines direct cancer-cell killing and immune activation. Macrophages are ideal for getting ferritin cages to cancer cells.

drawing in T and natural killer (NK) cells, activating nearby antigen presenting cells (APCs), notably dendritic cells (DCs), and repolarizing tumor-associated macrophages (TAMs) toward an M1 ...

Scientists at the Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) in Jena discovered a previously unknown function of immune cells in the ...