Gum disease caused by the bacteria Porphyromonas gingivalis is linked to worse multiple sclerosis (MS) in a mouse model of ...

It has been reported that various TRP channels are expressed in mammalian macrophages. TRP channels may be involved in various signaling pathways in the development of various systemic diseases ...

Doctors and researchers are exploring various approaches to tackle this pervasive health issue, from new medications to dietary interventions. But what if one of the most promising treatments relies ...

Although the precise mechanism of action remains incompletely understood, it is plausible that macrophages exert an influence on these pathological features. Macrophages, as a constituent of the human ...

Macrophages play a central role in the development of atherosclerotic cardiovascular disease (ASCVD), which encompasses coronary artery disease, peripheral artery disease, cerebrovascular disease, and ...

The spleen is a key site for extramedullary hematopoiesis that hosts a rare population of functional hematopoietic stem cells (HSCs). While the microenvironment that supports extramedullary ...

Recent advances in cancer research have underscored the critical role of myeloid cells in shaping tumor microenvironments (TME), influencing tumor progression, immune evasion, and therapeutic ...

1Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, VIB, Leuven, Belgium. 2Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, Department of ...

Nanoparticle-driven spleen remodeling allowed transplanted ... In mice, nanoparticle treatment expanded regulatory T cells and M2 macrophages while reducing effector T cells and pro-inflammatory ...

A collaboration between Wenzhou Medical University, Nanjing University, and the University of Macau has taken an unexpected turn in regenerative medicine by turning to the spleen, a lymphatic organ ...

Here, we provide an immunologist’s perspective on how the heart solves this challenge, which is in part by incorporating macrophages as an integral component of the myocardium. Cardiac macrophages ...