Factors induced during stress in the brain and/or skin, such as corticotropin-releasing hormone, neuropeptides, neurotrophins and α-melanocyte-stimulating hormone, can activate mast cells to ...

Sanofi acquires Blueprint Medicines Corporation for $9.1bn, gaining revenue-driving Aykavit and pipeline drug BLU-808 ...

The therapy targets mast cells by inhibiting receptor tyrosine kinase KIT, crucial for mast cell function and survival. Significant improvements in UAS7 and quality of life were observed.

The pharma giant is betting that Blueprint, whose research revolves around a certain kind of tyrosine kinase, will be a boost ...

Shares of Jasper Therapeutics rose after the company disclosed what it called positive data from a recent trial of its treatment for chronic mast cell diseases. The stock climbed 13%, to $6.32, in ...