Boys are more commonly affected. In children, infection often localises to the metaphysis of long bones due to their rich and slow-flowing blood supply. The distal femur, proximal tibia and proximal ...

A recent study identifies Neural EGFL-like 2 (NELL2), a secreted protein, as a key regulator of bone homeostasis, offering ...

This is a catastrophic injury, with extensive damage to the joint surface, fragmentation of the widened flare (metaphysis) of the distal radius, and damage to the shaft of the radius and/or the ...

Sequential reaming and metaphyseal cone reconstruction of both medullary canals was performed. Bone loss of the tibial metaphysis warranted the use of a 21-mm cone. On the femoral side, a 15-mm cone ...

The authors investigated KLF Transcription Factor 16 (KLF16) as an inhibitor of osteogenic differentiation, which plays a critical role in bone development, metabolism and repair. The results of the ...

This important work advances our understanding of CHMP5's role in regulating osteogenesis through its impact on cellular senescence. The evidence supporting the conclusion is convincing and the ...

This contribution is part of the special series of Inaugural Articles by members of the National Academy of Sciences elected in 2020. Contributed by Sean J. Morrison, April 16, 2021 (sent for review ...

The growing body of online, open access medical resources (eg, Orphanet and the National Organization for Rare Diseases) and the rising number of public initiatives 1 have greatly increased public ...

Whole body vibration with rest days could improve bone quality of distal femoral metaphysis by regulating trabecular arrangement He Gong, Rui Zhang, Jiazi Gao, Meng Zhang and Bei Liu et al. 13 July ...