A patient with CLL achieved a complete response using a methionine-restricted diet and oral recombinant methioninase in combination with chemotherapy.

In normal cells, oxidation of methionine to a methionine sulfoxide is reversed by an enzyme that removes the oxygen atom — that is, reduces it.

The protein, named methionine sulfoxide reductase A (MSRA), caught the attention of Dr. Chio and her colleagues due to its unusually low levels of expression in metastatic pancreatic cancer cells.

All living cells possess an intricate network of repair systems controlling the redox state of these residues that are highly prone to oxidation. Among them, methionine sulfoxide reductases (Msr) ...

Mimicking oxidation of Met35 by changing it for Gln caused complete loss of function, whereas mimicking oxidation of Met164 resulted in constitutive SOS activation and loss of recombination activity.

Chemists have reported a new method for separation of methionine sulfoxide diastereomers that opens up new opportunities for studying their roles in biological processes.

Oxidation of the sulfur atom in methionine is an important biomolecular reaction that can have a wide range of biological consequences depending on the context and the protein involved.

Oxidation of the sulfur atom in methionine is an important biomolecular reaction that can have a wide range of biological consequences depending on the context and the protein involved. Chemists ...

Proteins are made up of long chains of amino acids, and most proteins have one or more of the sulfur-containing amino acid methionine. Oxidation of the sulfur atom in methionine is an important ...