Inhibiting an overabundant enzyme saved a key component of a brain signaling pathway that is vital for motor control in a ...

Stanford researchers discovered that dialing down an overactive enzyme, LRRK2, can regrow lost cellular “antennae” in key ...

Determination of left–right asymmetry in mouse embryos is achieved by a leftward fluid flow (nodal flow) in the node cavity that is generated by clockwise rotational movement of 200–300 cilia ...

Cilia's secrets revealed using connectome data Date: January 15, 2025 Source: Howard Hughes Medical Institute Summary: By reexamining 3D images used to map the connections between brain cells ...

The result is the most detailed and comprehensive description to date of the cilia in this part of the mouse brain, including which cell types do or do not have cilia, ...

Primary cilia are required for vertebrate cells to respond to specific intercellular signals. Here we define when and where primary cilia appear in the mouse embryo using a transgenic line that ...

J ing Hughes, an endocrinologist at Washington University in St. Louis, was working late in the lab recently, imaging cilia in mouse pancreatic beta cells.These cilia, which are tiny hairlike ...

In recent years, researchers have been learning more about why cellular antennas called cilia are so important. Cilia can act as sensors of the cell's environment and can send and receive signals.

To analyze more primary cilia, Ott and her team examined publicly available vEM datasets of developing mouse cerebella. Because the GCs’ developmental stage corresponds to their depth in the tissue, a ...

Tiny hairs, or cilia, in a mouse embryo gyrate clockwise, setting up a leftward flow in the surrounding fluid. This fluid flow is then picked up by static cilia, called immotile cilia, located to the ...

Studies in the mouse visual cortex and cerebellum show structural differences in cilia and their developmental changes, which may influence disease understanding and treatment. This summary was ...