Stanford researchers discovered that dialing down an overactive enzyme, LRRK2, can regrow lost cellular “antennae” in key ...

Inhibiting an overabundant enzyme saved a key component of a brain signaling pathway that is vital for motor control in a ...

Cilia's secrets revealed using connectome data Date: January 15, 2025 Source: Howard Hughes Medical Institute Summary: By reexamining 3D images used to map the connections between brain cells ...

J ing Hughes, an endocrinologist at Washington University in St. Louis, was working late in the lab recently, imaging cilia in mouse pancreatic beta cells.These cilia, which are tiny hairlike ...

The result is the most detailed and comprehensive description to date of the cilia in this part of the mouse brain, including which cell types do or do not have cilia, ...

Cilia, the little "hairs" attached to almost all cells of the human body, ... Cryo-EM maps of human CPLANE complex (left) and of mouse CPLANE complex bound to MmRsg1 (right).

Tiny hairs, or cilia, in a mouse embryo gyrate clockwise, setting up a leftward flow in the surrounding fluid. This fluid flow is then picked up by static cilia, called immotile cilia, located to the ...

But the new results hint that abnormal cilia may be more widely involved in obesity. Earlier genetic studies have tied obesity to the MC4R gene, which the mouse study now shows to be important in ...

To analyze more primary cilia, Ott and her team examined publicly available vEM datasets of developing mouse cerebella. Because the GCs’ developmental stage corresponds to their depth in the tissue, a ...

Inhibition of LKKR2 may rescue neurons that are dying due to a type of Parkinson’s disease that is caused by a single genetic mutation.

This is a scanning electron microscopy image of cilia from mouse airway epithelia culture. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to ...