A model developed by LMU biophysicists demonstrates how biological processes form the convoluted internal architecture of the ...

AMSBIO has launched a comprehensive range of Quick-Neuron™ differentiation kits, designed to simplify and accelerate the ...

KRAKOW, Poland I June 12, 2025 I Ryvu Therapeutics (WSE: RVU), a clinical-stage drug discovery and development company focusing on novel therapies that ...

Acute myelogenous leukemia, or AML, remains one of the most aggressive blood cancers. Each year, around 44,000 people in the U.

TURKU, FI / ACCESS Newswire / May 27, 2025 / Faron Pharmaceuticals (HEL:FARON)(LSE:FARN) - New preclinical data published in Scientific Reports confirms CLEVER-1 inhibition by Bexmarilimab increases a ...

TURKU, FI / ACCESS Newswire / May 27, 2025 / Faron Pharmaceuticals (HEL:FARON)(LSE:FARN) - New preclinical data published in Scientific Reports confirms CLEVER-1 inhibition by Bexmarilimab increases ...

Single-cell RNA sequencing (scRNA-seq ... reflected both early developmental blocks and lineage-biased differentiation toward myeloid, lymphoid, and erythroid fates. Analysis showed that primitive ...

Though AML is a genetically heterogeneous disease, all its subtypes share a common feature: impaired differentiation of myeloid progenitor cells in the bone marrow. This differentiation block ...

The drug's preclinical performance, detailed in JCI Insights (2024), highlights its ability to induce myeloid cell differentiation and enhance anti-tumor activity, positioning it as a potential ...

AML is an aggressive blood cancer that originates in the bone marrow and is known to impair the differentiation of myeloid cells, which leads to overproduction of immature cells. The condition ...

This study shows that upon PU.1 downregulation myeloid cells ensure their survival by overexpressing a RUNX1-dependent stem cell- autophagy program. PU.1 preserves monomyeloid differentiation by ...