cells are promising candidates for targeting persistently infected CD4 + T cells in people with HIV-1 (PWH). However, chronicity of HIV-1 infection impairs NK cell functionality, requiring additional ...

Osteogenic differentiation is essential for bone development, metabolism, and repair; however, the underlying regulatory relationships among genes remain poorly understood. To elucidate the ...

However, a greater understanding of NK biology, coupled with the emergence of new technologies are leading to a resurgence of NK cell-based ... of induced pluripotent stem cells (iPSC) that ...

The ability to acquire high-quality NK cells in sufficient numbers represents a significant bottleneck in terms of NK cell application in adoptive immunotherapy. Induced pluripotent stem cells ...

A new type of cell-based immunotherapy shows promise for B-cell lymphomas and - due to innovations in manufacturing - could make future cellular immunotherapies less expensive and more accessible to ...

There’s use for pluripotent stem cells in disease diagnosis and treatment. Ultimately, Jing says, the hope is to both expand the giant panda population and make it healthier. The team’s ...

Human blood stem cells have been made in a laboratory for the first time, which could significantly improve how we treat certain types of cancer. The lab-grown cells have so far only been tested ...

Human-induced pluripotent stem cell-derived cardiomyocyte sheets can be a life-saving intervention for patients with advanced cardiovascular disease. Administration of immunosuppressive agents to ...

So in 2013, at a time when all eyes were on T cells, Rezvani shifted her research focus to NK cells. NK cells have a better safety record and unique features that make them good candidates for off ...