A study has found that an ancient protein motif that binds to nucleic acids is functionally "ambidextrous." This means that ...

Fujian Provincial Key Laboratory of Fire Retardant Materials, College of Materials, Xiamen University, Xiamen 361005, China Xiamen Key Laboratory of Fire Retardant Materials, College of Materials, ...

QRNAS is a software tool for fine-grained refinement of nucleic acid structures, dedicated to improving the quality of models generated by low- to medium-resolution methods commonly used, e.g., for ...

In the small molecule era, it was critical to control the placement of every atom and every bond within a particular structure. If one element were ... and spherical nucleic acids (SNAs). Developed by ...

Historically, the vast majority of pharmaceutical drugs have been meticulously designed down to the atomic level.

"In the small molecule era, it was critical to control the placement of every atom and every bond within a particular structure ... spherical nucleic acids (SNAs), chemoflares and megamolecules.

“In the small molecule era, it was critical to control the placement of every atom and every bond within a particular structure. If one element was ... structural nanomedicines: spherical nucleic ...

There has been a recent shift in how we think about the function of the genome to go beyond sequence to include structure ... to-telomere genomes, Nucleic Acids Research (2025).

Researchers, led by Penn State biologists, have comprehensively predicted the location of potential non-B DNA structures in ...