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Gut microbe enzyme with surprising metabolic capabilities offers new therapeutic possibilitiesThey discovered that levels of two molecules called oleoylethanolamide (OEA) and palmitoylethanolamide (PEA) were much lower in the guts of animals that had been colonized with microbial communities ...
In a world increasingly turning to pharmaceuticals for weight loss and metabolic control, a quieter contender is re-entering the conversation, one that has been in Mediterranean kitchens for centuries ...
Ethanolamides are proposed to be the endogenous ligands for GPR119, with oleoylethanolamide as the most potent endogenous GPR119 agonist identified to date.
The GLP-2–increased presence of CD36 at the apical membrane may be instrumental in transporting oleic acid as a substrate for the synthesis of oleoylethanolamide, a satiety factor.
N-acyl ethanolamines represent conserved lipophilic signaling molecules that function as endogenous ligands at G-protein-coupled receptors, ion channels, and nuclear receptors. Using a combination of ...
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