Figure 3: Analysis of spinal expression of oligodendrocyte markers and oligodendrocyte morphology in mice with inducible oligodendrocyte ablation (oDTR) and control littermates after diphtheria ...

These cells may be identified by their A2B5 + PSA-NCAM-phenotype (positive for the early oligodendrocyte marker A2B5 and negative for the polysialylated neural cell adhesion molecule). We used ...

They found more GFP-expressing cells in the mSOD1 animals than in control reporter mice, and many of the cells had dropped the PDGFαR marker in favor of the mature oligodendrocyte marker APC. No ...

Citation: Study reveals unique histone tag in oligodendrocyte progenitor cells, opening doors for advanced myelin repair therapies (2024, August 12) retrieved 25 May 2025 from https ...

While oligodendrocyte generation normally dwindles after the ... they might be visible on magnetic resonance imaging and serve as a marker for disease progression, Rothstein speculated. ALS ...

Multiple sclerosis is an inflammatory disease of the central nervous system that destroys myelin, oligodendrocytes, and axons. Since most of the lesions of multiple sclerosis are not remyelinated ...

About OPC1 OPC1 is an oligodendrocyte progenitor cell (OPC) transplant therapy designed to provide clinically meaningful improvements to motor recovery in individuals with acute spinal cord ...