Capstan Therapeutics scientists demonstrate that lipid nanoparticles can engineer CAR T cells within the body without ...

Expression profiles of villus and crypt cells are distinctly independent of dietary/genetic risk. Fig. S1 has details of data generation and analyses. Level of expression of Paneth cell markers, Fzd5, ...

Cell death is a biological phenomenon that occurs in all living organisms; nevertheless, excessive cell death has been linked to IBD, including increased immune and intestinal epithelial cell death ...

We thank Bruce Vallance for their gift of Il18 −/− mice. NJW was supported by both an Ontario Graduate Scholarship and Canadian Graduate Scholarship, and this project was funded by Grants from the ...

Paneth cells are located in the crypts of Lieberkühn in mammalian small intestines and are producing antimicrobial peptides to keep the microbiome under control. The genetic manipulation of Paneth ...