Research led by scientists from the Institute of Molecular Biology of Barcelona (IBMB) of the CSIC and the Bellvitge ...

Such dense actin polymerization induced by these large amounts of PtdIns (4,5)P 2 is critical for the induction of pseudopodia and for phagosomal cup formation, which results in the phagocytosis ...

Specifically, they have been able to see how zebrafish embryos use cells present on their surface, known as epithelial cells, to ingest and destroy bacteria through a process called phagocytosis ...

Upon exposure to the host cytosol, L. monocytogenes expresses the surface protein ActA that hijacks the host actin polymerization machinery, and allows bacteria to move intracellularly and to ...

Phagocytosis of complement-opsonized targets requires Mac-1 and induces apoptosis via NADPH oxidase-derived ROS-mediated activation of caspase-8 (21). This occurs despite ERK activation following ...

Actin barbed end-binding macrolides have been shown to inhibit cancer cell motility and invasion of extracellular matrix (ECM), evoking their potential utility as therapies for metastatic cancers.