Prostaglandin E2 (PGE2), a bioactive lipid derived from arachidonic acid, mediates a broad range of physiological processes ...

Scientists are aiming to determine the composition and topology of physiological Ashwell-Morell receptor ligands. Their findings will help uncover the receptor's still-hidden secrets.

These drugs are called agonists. They don't cause neurotransmitter levels to rise but instead increase activity by stimulating receptors. GABA agonists include: Yoga is generally believed to be ...

They don’t just generate text or images, but make decisions and act on them. So, to demonstrate agentic applications, we have compiled powerful real-world examples of AI agents in 2025. From ...

The effects that result depend on where the receptor is located and which endocannabinoid it binds to. For example, endocannabinoids might target CB1 receptors in a spinal nerve to relieve pain.

Recently, a new class of therapeutics that disable the neonatal Fc receptor (FcRn), which protects IgG from degradation, has emerged to treat IgG-mediated autoimmune disease. 4,5 Here, we review ...

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs ... for heart health and kidney function in people with diabetes. For example, research has shown that treatment with Ozempic, Trulicity ...

CD4 proteins act as receptors to recognize "foreign" agents that are presented ... Treg cells are tasked with limiting the potentially damaging effects of Th cells. For example, interleukin 17 ...

This patent highlight describes a series of novel 2-pyrrolidone derivatives that act as negative allosteric modulators (NAMs) of GluN2B-containing N-methyl-d-aspartic acid receptors (NMDARs). These ...

The authors suggest that it is related to sleep stage and serotonin acting at one type of serotonin receptor in the dentate gyrus ... across different brain areas and brain states. For example, ...