Mutations in gene promoters reveal specific pathway pathologies in pancreatic cancer Whole-genome sequencing reveals mutations outside of protein-coding regions Date: May 8, 2017 Source: Cold ...

DNA sequences that regulate expression of the insulin gene are located within a region spanning ~400 bp that flank the transcription start site. This region, the insulin promoter, contains a ...

A team of researchers unveils a novel, key aspect of enhancer-mediated regulation of gene expression and proposes a mechanism that explains the tight connection between gene enhancers and promoters.

Characterizing gene promoters and promoter–terminator combinations is crucial for maximizing the benefits of bioengineering applications in plants. However, traditional methods of ...

Suppressing protective genes: VPS72 adds chemical tags to the promoter of gene ATF3, which normally helps prevent cancer growth.

A recently developed system for switching on the activity of genes could improve treatments for a broad range of neurological diseases.

The dynamics of nucleosome formation and positioning in promoters may, for example, help to understand why some genes are highly expressed, such as those involved in normal or malignant growth ...

ASM led to significant changes in allelic expression ratios for the ISG15-Seed2 and MRPL52-PAM3 genes. The researchers were also interested in developing and characterizing highly specific ...

The Promoters of Gene Transcription By Science News Magazine Issue: Vol. 107 No. #21, May 24, 1975 ...

Suppressing protective genes: VPS72 adds chemical tags to the promoter of gene ATF3, which normally helps prevent cancer growth.