Collectively, the data from in vitro and in vivo studies using FUS, TDP-43, and C9orf72 models demonstrate that hUPF1 holds significant potential for treating the majority of patients with ALS and ...

In a new study published in Cell Reports, researchers at the University of Freiburg reveal how a disordered protein segment helps connect two key steps of gene expression: the reading of genes and the ...

To help achieve more precise control of gene therapy, engineers have designed a new control circuit that can keep gene expression levels within a target range. The method could be used to deliver ...

Welcome to The Impossible Build! Here, we take on massive, ambitious building projects that most would call impossible — and ...

This valuable study focuses on defining how the HSP70 chaperone system utilizes J-domain proteins to regulate the heat shock response-associated transcription factor HSF1. Using a combination of ...

The French biotechnology firm aims to develop therapies for various neurological conditions using its non-replicating HSV-1 ...

Vinay Prasad, a critic of the Food and Drug Administration, has been tapped as the agency’s top regulator of vaccines, gene ...

Smashing Pumpkins' Billy Corgan on his upcoming Machines of God tour, the long awaited 'Machina' box set, and his new Magnificent Others podcast.

Early fruit ripening is a valuable trait for grape cultivation, but the underlying epigenetic mechanisms have remained elusive.

Research reveals TAF2's disordered region links transcription and RNA editing, highlighting its role in gene expression regulation and nuclear organization.

Henry Johnson is well worth seeing, especially for fans of David Mamet. Interesting writing will always merit a trip to the ...