The renal tubular epithelial cells (TECs) represent the central cell type ... 1 Origin of proliferating tubule cells. A. The first hypothesis suggests that renal tubular repair originates from a ...

In a paper, "Renal macrophages monitor and remove particles from urine to prevent tubule obstruction ... of macrophages to surveil epithelial cells and intratubular environments.

The preclinical study showed, for the first time, the investigators claim, that human renal epithelial ... a cell-containing bioreactor component to recapitulate native renal tubule function ...

Several immunotherapies are now approved for the management of metastatic RCC. However, immunotherapy-based combination regimens are associated with high rates of treatment-related toxicities and do ...

In kidney morphogenesis, apical-basal polarization of renal epithelial cells is paramount for tubule formation and subsequent tissue functions like excretion and resorption. In kidney epithelium, ...

For example, under normal physiological conditions, most of the mammalian renal cells are arrested in G0 phase. However, Vogetseder et al. have found that a large number of rat epithelial cells in the ...

These data suggest that proximal tubules, and to a lesser-extent distal tubules ... We also demonstrated for the first time that renal tubular epithelial cells are a major source of IL-18 in this ...

Although several cellular defects have been associated with cystinosis, the mechanism linking cystinosin loss, and epithelial dysfunction remains largely unknown. CRISPR‐generated isogenic cystinotic ...

Human primary proximal tubule epithelial cells have a limited ... more insight into safety and suitability of these cells for applications in renal replacement therapies. The Masereeuw Research ...