Strikingly, the researchers also observed similar cilia defects in motor neurons from ALS patients with mutations in one of the most common genetic causes of ALS, C9orf72.

From these volumes, Ott and her team determined that primary cilia permanently disassemble as GC progenitors differentiate. Given that this disassembly occurs in postmitotic cells, the researchers ...

An image of cells in the contracted state is shown in Figure 4D. Figure 2 Scanning electron microscopy (SEM) micrographs of Paramecium caudatum prepared by different drying methods. (A, B) Cells ...

Using cryo-electron tomography, researchers have uncovered details of how the dynein motor protein drives cilia to beat. Understanding this motion may help to tackle health problems that affect ...

The first image of the structures that power human cilia -- the tiny, hairlike projections that line our airways -- has now been produced and it could lead to much-needed treatments for people ...

The first image of the structures that power human cilia – the tiny, hairlike projections that line our airways – has been produced by a team involving UCL researchers and could lead to much ...

A new PNAS study examined primary cilia in human islet cells using a multi-scale surface scanning electron microscope approach to obtain a three-dimensional (3D) image of their architecture.

This study has revealed the potentially important role of cilia in other parts of the body, such as on the liver and kidneys. Further investigation of these neuronal cilia and their axo-ciliary ...

A group of rare diseases called ciliopathies -- polycystic kidney disease notable among them -- emerge from defects in cilia. These are the tiny hairlike structures on the surface of almost every ...

Cilia, the little "hairs" attached to almost all cells of the human body, play a role in various cellular functions and cause diseases called ciliopathies when they are defective. Researchers from ...