A new platform comprehensively profiles CAR T-cells during manufacturing, revealing phenotypic shifts. This allows for ...

Background Follicular helper T (TFH) cells induce germinal center response to produce ... Our previous study has shown that ETV5 promotes murine TFH cell differentiation. However, its role in human ...

Poster Title: ARV-393, a PROteolysis TArgeting Chimera (PROTAC) BCL6 Degrader, is Efficacious in Preclinical Models of Diffuse Large B-Cell Lymphoma, Nodal T-Follicular Helper Cell Lymphoma, and ...

In an interview with Targeted Oncology TM, Ciara Freeman, MD, medical oncologist at Moffitt Cancer Center, discusses anitocabtagene autoleucel (anito-cel), an autologous BCMA-directed CAR T-cell ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Subcutaneous LCMV infection induces T H 1 cell ...

“Neuropeptide signaling orchestrates T cell differentiation.” How would you summarize your study for a lay audience? T helper (TH) cells are essential immune cells that help other immune cells ...

This metabolic alteration was directly correlated with reduced differentiation of helper T cells, which are essential for coordinating immune responses. "Our findings reveal that DOCK8 mutations ...

The authors analyze the roles of PD-1 in the early stages (pre-activation) of T cell differentiation and show that naïve CD4+ T cell differentiation is altered, especially Th2 differentiation is ...

This study, led by Dr. Panpan Jiang and collaborators at Tongji Medical College, explores the critical role of the Dedicator of Cytokinesis 8 (DOCK8) gene in the differentiation of helper T cells ...

T follicular helper cells (Tfh ... This is a group of proteins that initiates and regulates the growth and differentiation of cells. The Bonn team led by Prof. Dr. Dirk Baumjohann has now ...

During a bout of influenza, B cells ... produced by T follicular helper cells, or Tfh cells, after intranasal influenza infection is required to initiate the path of B cell differentiation into ...