Lyell Immunopharma announced new clinical data Tuesday from a Phase I/II trial of its dual-targeted CD19/CD20 CAR T-cell therapy for relapsed or refractory large B-cell lymphoma. The company ...

Despite advances, the roles of genetics and microenvironment in CLL are not fully understood, and curative treatments may hinge on a dual approach targeting both.

Kennedy researchers have uncovered key design parameters for bispecific T-cell engagers (TcEs)—a class of cancer ...

Analysis revealed that patients with T-cell exhausted archetype tumors had significantly higher rates of progressive disease ...

Announcing a new article publication for Zoonoses journal. Because varicella zoster virus (VZV) infections are continually ...

Influenza virions can take a variety of shapes, from the classic spherical or kidney bean morphology found in most ...

Background Current treatments with tyrosine kinase inhibitors and immune checkpoint inhibitors have limited efficacy for hepatocellular carcinoma (HCC) due to drug resistance. Emerging therapies such ...

Memorial Sloan Kettering Cancer Center investigators report that T cell interferon-γ (IFNγ) orchestrates a dendritic-cell–natural-killer-cell circuit that suppresses leptomeningeal metastases ...

The emergence of machine learning and high-content microscopy suggests potential to more comprehensively define CF activation beyond simply staining α-SMA. Here, we coupled Cell Painting 4 with a ...

Using this approach, Neal et al. were able to produce the first open-source genome-wide perturbation atlas of cell morphology in human cells. The atlas contains 3 genome-wide genotype-phenotype maps ...

Cell morphology describes the shape, size, structure and appearance of a cell, including the arrangement of organelles within the cell. The morphology of a cell is a rich source of information about ...