Digging deeper, the team uncovered the mechanism: HYAL1’s breakdown of HA redirects cellular Uridine diphosphate N-acetylglucosamine (UDP-GlcNAc), reducing a key modification (O-GlcNAcylation ...

Increased Risk of Adverse Reactions in Patients with Reduced UGT1A1 Activity: Patients homozygous for the uridine diphosphate-glucuronosyl transferase 1A1 (UGT1A1)*28 allele are at increased risk for ...

A comprehensive glucose metabolic gene qPCR arrays in PFKFB3 silenced HSS-ECs, and PFKFB3-knock-down ischemic muscle versus respective controls identified UGP2 (uridine diphosphate-glucose ...

Introduction: The uridine diphosphate (UDP)-glycosyltransferase (UGT) family is the largest glycosyltransferase family, which is involved in the biosynthesis of natural plant products and response to ...

Danone has filed a patent for a method of improving and prolonging blood plasma uridine levels and treating disorders associated with impaired uridine availability. The method involves orally ...

State Key Laboratory of Crop Stress Biology for Arid Areas, Key Laboratory of Plant Protection Resources and Pest Management of Ministry of Education, Key Laboratory of Integrated Pest Management on ...

A recent study published in the journal Nature identified uridine-derived ribose as the fuel for pancreatic ductal adenocarcinoma (PDA) in glucose-restricted conditions. The PDA tumor ...

Figure 1. (L) Glucose, the primary fuel of the body. (R) The chemical structure of uridine diphosphate, an alternate fuel for pancreatic cancer cells. Note that uridine diphosphate contains ribose, ...