BRD4 or VHL NanoLuc fusions were individually expressed in HEK293 cells. Intracellular engagement was quantified using TE BRD Tracer 02 or VHL tracer, following a 3-hr equilibration (Figures 3A & 3B).

Researchers at Oncopia Therapeutics Inc. (dba Proteovant Therapeutics Inc.) and University of Michigan have synthesized proteolysis targeting chimera (PROTAC) compounds comprising a Von Hippel-Lindau ...

Motif FoodWorks launches HEMAMI heme-binding protein delivering the ‘flavor and aroma of real meat,' receives GRAS no questions letter from FDA By Elaine Watson 08-Dec-2021 Last updated on 09 ...

We also find that dynamically remodeled 5-HT chromatin regions are enriched for the GGAA/T binding motif of ETS domain transcription factor Pet1 that is important for 5-HT specific gene expression.

Motif FoodWorks has submitted a GRAS notification for myoglobin, a heme-binding protein found in the muscle tissue of cows that Motif is expressing in a genetically engineered yeast strain. The ...