Satellos Bioscience Chief Scientific Officer discusses early-stage trials of the company's Duchenne muscular dystrophy drug, ...

In many genetic diseases, a small error in the DNA code can have devastating effects. These errors, called nonsense mutations ...

Obesity can have a distinct impact on the absorption, effectiveness and excretion of antibiotics, medications that have been in use for more than 80 years, but only now have consensus guidelines been ...

Medications like zoledronic acid (Reclast ... while others damage kidney cells directly. Examples include aminoglycosides, vancomycin, acyclovir, and tenofovir (used in HIV treatment).

An international team of researchers, including scientists of the University of Groningen, has now demonstrated how the antimalarial drug mefloquine can enhance the effect of aminoglycosides, another ...

An international team of researchers, including scientists of the University of Groningen, have now demonstrated how the antimalarial drug mefloquine can enhance the effect of aminoglycosides ...

They treat severe infections in people of all ages. Aminoglycoside antibiotics are ototoxic drugs that can cause hearing loss. They affect the inner ear, and some people may develop tinnitus.

This makes it difficult for researchers to assess how common it is as a side effect of aminoglycosides. Chemotherapy drugs target and kill different types of cancer cells. The type of chemotherapy ...

However, the market faces significant challenges due to the adverse side effects associated with aminoglycosides, such as ototoxicity and nephrotoxicity, which can limit their use. Furthermore, the ...

Aminoglycoside antibiotics are well-known to cause ototoxicity, particularly hearing loss. Other antibiotics can also cause significant ototoxicity but the effects of these drugs on hearing and ...