Are there key genes involved in TKI resistance in ccRCC? What mechanisms are associated with this development? A research team, led by Professor Ben Liu from the Department of Urology at the First ...

Phosphorylation is the enzymatic process through which a phosphate group is added via an ester bond, generally by a kinase, to either a small molecule or a protein. Protein phosphorylation is ...

Scientists have made a potentially "life-changing" discovery that could lead to new drugs for treating Parkinson's disease.

Experts have known for several decades that the PINK1 protein is directly linked to Parkinson’s disease – the fastest growing ...

Scientists have known for years that certain proteins were associated with Parkinson’s disease. But in a recent paper ...

WEHI researchers have solved a decades-long mystery by determining the structure of human PINK1, a key protein linked to ...

Melbourne-based researchers at the Walter and Eliza Hall Institute (WEHI) at the Parkinson's Disease Research Centre have ...

Recent work in The EMBO Journal describes a new hybrid post-translational modification of proteins, composed of a poly-ubiquitin chain that is attached to a target protein via a mono-ADP-ribose (MAR) ...

Study reveals the structure of PINK1 protein, offering fresh hope for Parkinson's patients through potential targeted ...

Researchers have revealed for the first time how a key protein linked to Parkinson's mutates, leads to cell death in the ...

Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Science, Northwest University, Xi’an 710000, China ...