Study reveals the structure of PINK1 protein, offering fresh hope for Parkinson's patients through potential targeted therapies that address root causes.

WEHI researchers have made a huge leap forward in the fight against Parkinson’s disease, solving a decades-long mystery that paves the way for development of new drugs to treat the condition. First ...

A form of Parkinson’s disease caused by mutations in a gene known as PINK1 has long been labelled rare. But our research shows it’s anything but – at least for some populations. Our meta-analysis ...

A new study reveals that T cells mistakenly attack brain cells expressing PINK1, contributing to Parkinson’s disease. The research also highlights a striking sex difference, with men showing a sixfold ...

In this way, PINK1 has been known to play an important role in the early onset of Parkinson's disease, and scientists have been able to capture differing images of they way it is activated.

In Parkinson’s disease, mutations in PINK1 and Parkin can result in the accumulation of damaged mitochondria in the brain, leading to the tremors and stiffness that are the hallmarks of the ...

Since mutations in the PINK1 and DJ-1 genes were found 825 NE 13th St., Oklahoma City to cause autosomal recessive forms of Parkinson disease (PD), scientists have wondered what these genes might tell ...

Scientists have made a potentially “life-changing” discovery that could pave the way for new drugs to treat Parkinson’s disease. Experts have known for several decades that the PINK1 protein ...

PINK1 protein discovery could accelerate Parkinsons disease drug development New insights into mitochondria may pave the way for innovative treatments in neurodegenerative disorders.

This article reviews the PINK1 protein product, which has been implicated in several functions, mostly aimed at protecting neuronal cells against different types of stress.

Recessive mutations in the PINK1 gene are associated with cases of familial Parkinson disease (PD), so this research provides further support for a mitochondrial involvement in this condition.