Restoring the function of pathogenic PINK1 mutations found in Parkinson’s patients with small molecule drugs, is a paradigm shift in Parkinson’s disease.

Misbehaving T cells light up long before Parkinson’s symptoms show, zeroing in on vulnerable brain proteins. Their early ...

Your T cells work hard to fight disease. Unfortunately, "friendly fire" from T cells can sometimes harm the body's healthy tissues.

Bangladeshi-origin neurologist Miratul Muqit has been appointed as the inaugural director of the United Kingdom's National ...

A University of Dundee expert has been appointed to lead a new centre that will drive research to better understand the ...

Progenra Inc. reports that it has discovered a new class of small-molecule PINK1 activators that restore function in mutant forms of the PINK1 kinase, a key mitochondrial regulator whose dysfunction ...

Parkinson's disease occurs when brain cells that produce an important hormone called dopamine begin to die off or become ...

Inactivating mutations in human Parkin, a ubiquitin E3 ligase and PINK1, a kinase, genes present a significant population of inherited Parkinson’s disease.

A progressive neurological disorder affecting 10 million people globally, Parkinson’s can cause disruptive symptoms such as ...