Genetic mutations occur everyday in our cells, but the vast majority of them are repaired. New research finds DNA repair is not on PAR in HD cells, causing mutations to build up in people with HD.

Huntington’s disease disrupts genetic "traffic lights," keeping genes green when they should be red. These genetic traffic jams may act to speed brain cell aging and faulty traffic cops ...

Hidden twists in the Huntington’s disease gene could shift symptoms by over a decade! Scientists have uncovered rare “genetic dams” that shape when HD begins - sometimes dramatically ...

For many with Huntington’s disease, recognising faces, navigating familiar places, or reading can be difficult. Scientists studied how and when HD affects how the brain processes what we see—crucial ...

Votoplam belongs to a class of drugs known as splice modulators. The drug can be taken as a daily pill - a convenient and non-invasive method of delivery. The drug is a chemical that changes how the ...

Imagine a busy intersection - traffic is carefully orchestrated with different colored lights, telling drivers when to stop and when to go. If a signal turns yellow, drivers know that the light is in ...

Dr. Sarah Hernandez is the Director of Research Programs at the Hereditary Disease Foundation (HDF). She carried out her ...

In plain language. Written by scientists. For the global HD community.