Neuro-evolutionary evidence for a universal fractal primate brain …
Sep 30, 2024 · This study presents valuable framework and findings to our understanding of the brain cortex as a fractal object. Based on detailed methodology, the evidence provided on the stability of its shape property within 11 primate species is convincing, as well as the scale-specific effects of ageing on the human brain.This study will be of interest to neuroscientists interested in brain morphology ...
Proteomic landscape of tunneling nanotubes reveals CD9 and …
Sep 9, 2024 · Tunneling nanotubes (TNTs) are thin membranous conduits, supported by F-actin that form continuous cytoplasmic bridges between cells over distances ranging from several hundred nm up to 100 µm (Rustom et al., 2004; Sartori-Rupp et al., 2019).They allow cell-to-cell communication by facilitating the transfer of different cargoes directly from cytoplasm to cytoplasm of the connected cells ...
Science Forum: Antibody characterization is critical to enhance
Aug 14, 2024 · Antibodies are critical reagents used in a variety of assays and protocols in biomedical and clinical research. The ability to detect, quantify, enrich, localize, and/or perturb the function of a target protein – even when present in a complex protein mixture, such as a cell lysate or tissue slice, or even in an intact organism – is key to many biomedical research studies.
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eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that encourages and recognises the most responsible behaviours in science. eLife Sciences Publications, Ltd ...
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Dec 16, 2024 · eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that encourages and recognises the most responsible behaviours in science. eLife Sciences Publications, Ltd is a limited liability non-profit non-stock corporation incorporated in the State of Delaware ...
How to measure and evaluate binding affinities | eLife
Aug 6, 2020 · We analyzed 100 papers reporting K D or ‘apparent K D ’ values of RNA/protein interactions. Measurements were evaluated based on two criteria: demonstrating equilibration (horizontal axis) and controlling for titration (vertical axis).
About - eLife
eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that encourages and recognises the most responsible behaviours in science.
Gene Fusion: Decoding the identity of rare tumors | eLife
Oct 7, 2024 · Gene fusions are common mutations that have been linked to several types of cancer, most notably chronic myelogenous leukemia, which is a result of the BCR gene on chromosome 22 fusing with the ABL gene on chromosome 9 (Nowell and Hungerford, 1960).Identifying fusion genes, and investigating the molecular behavior of the chimeric fusion proteins that arise from these mutations, may help with ...
About | eLife Assessments · eLife
eLife changed its approach to peer review in 2023 to better convey the assessments made by editors and reviewers. Every Reviewed Preprint published in the journal now includes an eLife Assessment written by the editor who oversaw the review process and the peer reviewers.
Microbiome: Balancing microbial composition through diet | eLife
Nov 20, 2024 · The gut of animals is a complex ecosystem consisting of trillions of bacteria and other microorganisms that are unique to every individual. Infants can inherit their first gut bacteria through vaginal birth and breastfeeding, and the microbiome is later reshaped through diet (Ames et al., 2023).The gut microbiome helps to break down and enhance the absorption of nutrients like carbohydrates ...